Maria Carmina Santiago
University of the Philippines, Philippines
Title: A case of uterine tumor resembling ovarian sex cord stromal tumor
Biography
Biography: Maria Carmina Santiago
Abstract
This is a case of a 42 G1P0 (0010), presenting with abnormal uterine bleeding and secondary infertility, who underwent total hysterectomy for myoma uteri. Histopathology, however, revealed a uterine tumor resembling ovarian sex-cord stromal tumor. Uterine tumors resembling ovarian sex-cord stromal tumors (UTROSCTs) are rare neoplasms with less than 100 documented cases, first described by Morehead and Bowman in 1945. They were classified by Clement and Scully into two groups: the first included those whose were less than 50% sex-cord like tissue (endometrial stromal tumor with sex cord-like elements, ESTSCLE or Type I) and the second whose tissue were almost completely sex-cord like tissue (classic UTROSCT or Type II). These tumors are typically benign, though some cases (those classified as Type I) are more aggressive. On immunohistochemistry, the tumor showed positivity for WT1, CD99, vimentin, and CK, classifying it as Type II. This confers a better prognosis for this patient.